Expression patterns of miR-146a and miR-146b in mastitis infected dairy cattle
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- 作者：Xing Ping Wanga ; b ; 1 ; huaswxp@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Zhuo Ma Luorenga ; b ; 1 ; Lin Sen Zana ; zanlinsen@163.com" class="auth_mail" title="E-mail the corresponding author ; Sayed Haidar Abbas Razaa ; Feng Lib ; Na Lib ; Shuan Liub
- 关键词：microRNA ; miR-146a ; miR-146b ; Mastitis ; Dairy cattle
- 刊名：Molecular and Cellular Probes
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：30
- 期：5
- 页码：342-344
- 全文大小：297 K
文摘
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We identified a significant upregulation of miR-146a/b in bovine mammary tissues challenged with S. aureus or E. coli.
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We identified a significant upregulation of miR-146a/b in mammary gland tissues with subclinical or clinical mastitis.
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MiR-146a/b were not significant expression in blood from cows challenged with S. aureus or E. coli compared to healthy cows.
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MiR-146a/b might target on TRAF6 and IRAK1 gene, and might be involved in 20 immunological pathways.
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MiR-146a/b are the potential moderators of bovine mammary inflammation.