A reference electrode-free electrochemical biosensor for detecting MMP-9 using a concentric electrode device

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• 作者：JaeWoong Lee^a ; ¹Author Vitae ; Jun Yeon Yun^a ; ¹Author Vitae ; Won Cheol Lee^a ; ¹Author Vitae ; Seongwook Choi^aAuthor Vitae ; JaeHeung Lim^aAuthor Vitae ; Hyeri Jeong^bAuthor Vitae ; Dong-Sik Shin^b ; ^c ; ^{dshin@sm.ac.kr}Author Vitae ; Young June Park^a ; ^{ypark@snu.ac.kr}Author Vitae
• 关键词：Electrochemical biosensor ; Concentric electrode device ; Matrix metalloproteinase (MMP) ; Methylene blue ; Peptide substrate
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：240
• 期：Complete
• 页码：735-741
• 全文大小：2491 K
• 卷排序：240

文摘

A reference electrode-free two electrode system was developed for electrochemical biosensors. An MB-peptide was immobilized on the concentric electrode devices to detect protease. MMP-9 was detected by measuring the electrical tunneling of remaining MB-peptide on the working electrode.