Early repolarization pattern in the general population: Prevalence and associated factors

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• 作者：Guo-Zhe Sun ; Ning Ye ; Yin-Tao Chen ; Ying Zhou ; Zhao Li ; Ying-Xian Sun ; ^{yxsun@mail.cmu.edu.cn}
• 关键词：Early repolarization pattern ; Risk factors ; Electrocardiography ; Epidemiology
• 刊名：International Journal of Cardiology
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：230
• 期：Complete
• 页码：614-618
• 全文大小：365 K
• 卷排序：230

文摘

To evaluate the prevalence of early repolarization pattern (ERP) in the general rural Chinese population and identify the contributing risk factors.MethodsA cross-sectional study of 11,956 permanent residents of Liaoning Province ≥ 35 y of age was conducted between January and August 2013 (response rate 85.3%). ERP was diagnosed if there was J-point elevation of ≥ 0.1 mV in ≥ 2 leads in the inferior (II, III, aVF) or lateral (I, aVL, V4–6) territory, or both. Risk factors for ERP were evaluated with a stepwise logistic regression analysis.ResultsThe overall prevalence of ERP was 1.3%, and it was higher in men than women (2.6 vs. 0.2%, P < 0.001), decreasing with increasing age. Percent of ERP positive in lateral leads, inferior, and both was 73.0%, 15.3%, and 11.7%, respectively. Stepwise logistic regression demonstrated that independent clinical factors for ERP included age (odds ratio [OR] 0.68; P < 0.001), male sex (OR 17.09; P < 0.001), systolic blood pressure (SBP) (OR 0.77; P = 0.022), stroke (OR 0.14; P = 0.055), RR interval (OR 1.27; P = 0.001), QTc interval (OR 0.76; P = 0.008), QRS duration (OR 0.67; P = 0.001), Cornell voltage (OR 0.28; P < 0.001), and Sokolow-Lyon voltage (OR 2.03; P < 0.001).ConclusionsAlthough the prevalence of ERP in general rural Chinese population is low, younger age, male sex, lower SBP, non-stroke history, longer RR interval, shorter QTc interval, shorter QRS duration, lower Cornell voltage, and higher Sokolow-Lyon voltage are independent risk factors.