Construction of an Advanced Taxane Synthesis Intermediate with an Oxygenated B-ring and a Non-Aromatic C-Ring through Intramolecular Pinacol Coupling at C-1-C-2

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• 作者：Swindell ; Charles S. ; Fan ; Weiming
• 刊名：Tetrahedron Letters
• 出版年：1996
• 出版时间：April 1, 1996
• 年：1996
• 卷：37
• 期：14
• 页码：2321-2324
• 全文大小：211 K

文摘

Advanced taxane synthesis intermediate 4 is available through a thirteen-step sequence wherein the key step is a stereoselective intramolecular pinacol coupling that joins C-1-C-2 within the eight-membered B-ring.