Adenovirus-vectored foot-and-mouth disease vaccine confers early and full protection against FMDV O1 Manisa in swine

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• 作者：Ignacio Fernandez-Sainz^a ; ^b ; Gisselle N. Medina^a ; ^c ; Elizabeth Ramirez-Medina^b ; ^c ; Marla J. Koster^a ; Marvin J. Grubman^a ; Teresa de los Santos^a ; ^{teresa.delossantos@ars.usda.gov}
• 关键词：FMDV ; Adenovirus ; O1Manisa ; Foot-and-mouth ; Disease ; Cross-protection ; Ad5-FMD ; Vaccine ; Swine
• 刊名：Virology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：502
• 期：Complete
• 页码：123-132
• 全文大小：1542 K
• 卷排序：502

文摘

Ad5-O1Manisa displays high potency. Ad5-O1Manisa vaccine can fully protect swine against FMD at 7 days post vaccination. Animals develop protective levels of antibodies against FMDV O Mya 98 topotypes.