Notch1 signalling inhibits apoptosis of human dental follicle stem cells via both the cytoplasmic mitochondrial pathway and nuclear transcription regulation
刊名:The International Journal of Biochemistry & Cell Biology
出版年:2017
出版时间:January 2017
年:2017
卷:82
期:Complete
页码:18-27
全文大小:3770 K
卷排序:82
文摘
Notch1 activation inhibits the apoptosis of HDFSCs. Notch1 increases cytoplasmic anti-apoptotic effects via the mitochondrial pathway. Notch1 inhibits apoptosis by down-regulating the p53 gene expression in nucleus.