The first meta-analysis of TEMPS score across psychiatric disorders, their relatives, and healthy controls.
26 studies, 2025 patients with BD, 1283 with MDD, 56 with ADHD, 43 with BPD, 436 relatives of BD, and 1757 HCs.
Cyclothymic,and irritable TEMPS scores develop on a continuum, from HCs through MDD to BD.
Cyclothymic, irritable and anxious scores develop on a continuum from HCs, through BD relatives to BD.
No difference in any TEMPS score between BD and ADHD.