Dietary lipids alter the effect of steroids on transport of glucose after intestinal resection: Part II. Signalling of the Response

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• 作者：Aducio L. Thiesen ; Kelly A. Tappenden ; Mike I. McBurney ; M. Thomas Cl ; inin ; Monika Keelan ; Ben K. Thomson ; Gary E. Wild ; Alan B. Thomson
• 关键词：Tissue engineering ; mesenchymal stem cells ; bone marrow-derived stromal cells ; cartilage ; tracheal malformations ; fetal surgery ; congenital anomalies ; transplantation
• 刊名：Journal of Pediatric Surgery
• 出版年：2003
• 出版时间：April 2003
• 年：2003
• 卷：38
• 期：4
• 页码：575-578
• 全文大小：316 K

文摘

Background/Purpose: The authors[apos ] 15-year experience with children shows a high percentage of recurrence of functional constipation (FC) with conventional treatment. These data, confirmed in the international literature, led them to develop a new therapeutic approach. The aim of this study was to achieve intestinal control and avoid recurrence of FC in children through use of medical-psychological treatment. Methods: The authors studied 25 children (18 boys; mean age, 4.7 years; range, 2.10 to 7), 20 % of whom had anal fissure, 30 % retentive soiling, 52 % pain on defecation, and 88 % fecal retention owing to FC. Children and parents were questioned about eating and sleeping habits, school, toilet training, and daily routine. Treatment included increasing water and fiber intake, laxatives, and family therapy including making rules and working on autonomy and paternal role. Results: Mean onset of FC was 3.5 years, after [ldquo ]stressful events[rdquo ] in 88 % . The questionnaire shows that 68 % lacked parental autonomy and authority; 84 % of children decided on their own about eating habits and sleeping; 68 % had a [ldquo ]peripheral[rdquo ] father with a mother-child symbiotic relationship. After one month of therapy, 92 % of children showed a modification of at least 2 behavioral patterns; after 3 months, 88 % had regular bowel movements. During follow-up (range, 6 to 28 months), 48 % had 2 or 3 recurrent episodes. After one year, 68 % had reinforced the new behavioral patterns with resolution of the pathologic aspects. Conclusions: A multidisciplinary approach in the treatment of childhood functional constipation showed consistent therapeutic results by making rules and by equalizing family roles. J Pediatr Surg 38:819-823. [copy ] 2003 Elsevier Inc. All rights reserved.