Impact of an endorectal coil for 1H-magnetic resonance spectroscopy of the prostate at 3.0 T in comparison to 1.5 T: Do we need an endorectal coil?

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• 作者：Maximilian K.M. Hoffner ^{Maximilian.Hoffner@gmx.net" class="auth_mail" title="E-mail the corresponding author} ; Frank Huebner ^{Frank.Huebner@kgu.de" class="auth_mail" title="E-mail the corresponding author} ; Jan Erik Scholtz ^{Janerikscholtz@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Stephan Zangos ^{Zangos@em.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author} ; Boris Schulz ^{Boris.Schell@googlemail.com" class="auth_mail" title="E-mail the corresponding author} ; Wolfgang Luboldt ^{luboldt@screening.org" class="auth_mail" title="E-mail the corresponding author} ; Thomas J. Vogl ^{t.vogl@em.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author} ; Boris Bodelle ; ^{bbodelle@googlemail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Prostate ; Proton MR Spectroscopic Imaging ; Endorectal coil ; Signal-to-noise ratio ; Diagnostic suitability ; 3.0  ; T MRSI
• 刊名：European Journal of Radiology
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：85
• 期：8
• 页码：1432-1438
• 全文大小：1507 K

文摘

To evaluate the influence of endorectal coil (ERC) regarding spectral quality and diagnostic suitability and diagnostic performance in 3.0 T 1H-magnetic resonance spectroscopy imaging (MRSI) compared to 1.5 T MRSI.

Materials and methods

The study was approved by the Institutional Review Board. MRSI of the prostate was performed on 19 patients at 1.5 T with ERC (protocol 1), at 3.0 T with a disabled ERC (protocol 2) and at 3.0 T with ERC (protocol 3). Age, weight, body size, body-mass-index, prostate volume, time between measurements, diagnostic suitability of spectra, histopathological results after biopsy of cancer suspect lesions (CSL), sensitivity and specificity were evaluated. Signal-to-noise ratio (SNR) was calculated and compared using semiparametrical multiple Conover-comparisons. Correlations between SNR and prostate volume and BMI were indicated using Pearson correlation coefficient. Distribution of SNR was evaluated for prostate quadrants.

Results

Diagnostic suitable spectra were achieved in 76 % (protocol 1, 100% in CSL), 32 % (protocol 2, 59% in CSL) and 50 % (protocol 3, 80% in CSL) of the voxels. SNR was significantly higher in protocol 3 compared to protocol 2 and 1 (93,729 vs. 27,836 vs. 32,897, p < 0.0001) with significant difference between protocol 2 and 1 (p < 0.023). Highest SNR was achieved in the dorsal prostate (protocols 1 and 3; p < 0.0001). Sensitivity at 3.0 T was higher with use of ERC. Specificity was highest at 1.5 T with ERC.

Conclusion

The ERC improves the diagnostic suitability and the SNR in MRSI at 3.0 T. Less voxels at 3.0 T with disabled ERC are suitable for diagnosis compared to 1.5 T with ERC. MRSI at 3.0 T with ERC shows the highest SNR. SNR in dorsal quadrants of the prostate was higher using ERC.