Detection of tissue factor-positive extracellular vesicles by laser scanning confocal microscopy

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• 作者：Yohei Hisada^a ; ^b ; Alyson C. Auriemma^a ; Wyeth Alexander^a ; Cihan Ay^a ; ^c ; Nigel Mackman^a ; ^b ; ^{nmackman@med.unc.edu}
• 关键词：Cancer ; Extracellular vesicles ; Laser scanning confocal microscopy ; Tissue factor
• 刊名：Thrombosis Research
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：150
• 期：Complete
• 页码：65-72
• 全文大小：1527 K
• 卷排序：150

文摘

There are few methods to visualize surface protein on extracellular vesicles (EVs). Tissue factor-positive EVs were visualized by laser scanning confocal microscopy (LSCM). Tissue factor-positive EVs were detected in plasma samples from pancreatic cancer patients.