The use of heparin chemistry to improve dental osteogenesis associated with implants

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• 作者：Sang Jin Lee^a ; ¹ ; Min Soo Bae^b ; ¹ ; Deok Won Lee^c ; Dong Nyoung Heo^d ; Donghyun Lee^a ; Min Heo^a ; Seoung-Jin Hong^e ; Joohyoung Kim^e ; Wan Doo Kim^f ; Su A Park^f ; ² ; ^{psa@kimm.re.kr} ; Il Keun Kwon^b ; ² ; ^{kwoni@khu.ac.kr}
• 关键词：Dental titanium implant ; Heparin ; Growth/differentiation factor-5 ; Periodontal ligament stem cells ; Dental bone tissue regeneration
• 刊名：Carbohydrate Polymers
• 出版年：2017
• 出版时间：10 February 2017
• 年：2017
• 卷：157
• 期：Complete
• 页码：1750-1758
• 全文大小：2877 K
• 卷排序：157

文摘

Titanium surface was developed to selectively graft the polymer using bioactive chemistry. The developed hybrid titanium disc showed outstanding in vitro osteo-integration activities. The surface modified titanium implant exhibited significant bone tissue regeneration in a rabbit model.