Molecular evolution of respiratory syncytial virus subgroup A genotype NA1 and ON1 attachment glycoprotein (G) gene in central Vietnam

详细信息    查看全文

• 作者：Keisuke Yoshihara^a ; ^b ; Minh Nhat Le^a ; ^c ; Koo Nagasawa^d ; Hiroyuki Tsukagoshi^e ; Hien Anh Nguyen^c ; Michiko Toizumi^a ; Hiroyuki Moriuchi^f ; ^g ; Masahiro Hashizume^a ; Koya Ariyoshi^h ; Duc Anh Dang^c ; Hirokazu Kimura^d ; Lay-Myint Yoshida^a ; ^{lmyoshi@nagasaki-u.ac.jp}
• 关键词：MCMC ; Markov Chain Monte Carlo ; AICM ; Akaike's Information Criterion through MCMC ; ESS ; effective sample size ; MCC ; Maximum Clade Credibility ; HPD ; highest probability density ; tMRCA ; time to the most recent common ancestor ; BSP ; Bayesian Skyline Plot ; EPS ; effective population size ; ML ; Maximum Likelihood ; SLAC ; Conservative Single Likelihood Ancestor Counting ; FEL ; Fixed Effects Likelihood ; IFEL ; Internal Fixed Effects Likelihood ; MEME ; Mixed Effects Model for Episodic Diversifying Selection
• 刊名：Infection, Genetics and Evolution
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：45
• 期：Complete
• 页码：437-446
• 全文大小：894 K
• 卷排序：45

文摘

Shifting patterns of RSV-A NA1 lineages were observed in 2010–2012 seasons. RSV-A ON1 lineage 1 with E262K appeared as the major genetic cluster in 2012. Vietnamese RSV-A ON1 and NA1 were evolving with the faster substitution rates. N-glycosylation patterns within G gene of Vietnamese NA1 shifted every year. N-glycosylation pattern of Vietnamese NA1 and ON1 strains were distinct.