Xenin-induced feeding suppression is not mediated through the activation of central extracellular signal-regulated kinase signaling in mice
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- 作者：Eun Ran Kim ; Pei San Lew ; Alexandra Spirkina ; Tooru M. Mizuno ; tooru.mizuno@umanitoba.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Gut hormone ; Feeding ; Hypothalamus ; Signaling ; Neurotensin ; MAPK
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：312
- 期：Complete
- 页码：118-126
- 全文大小：2059 K
文摘
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Xenin increased the number of pERK1/2-immunoreactive cells in the mouse hypothalamus.
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Xenin increased pERK1/2 levels in mouse hypothalamic cell lines expressing Ntsr1.
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U0126 pre-treatment did not affect xenin-induced feeding suppression in mice.
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