Enantioselective bioreduction of acetophenone and its analogous by the fungus Trichothecium sp.
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- 作者：Mandal ; Deendayal ; Ahmad ; Absar ; Islam Khan ; M. ; Kumar ; Rajiv
- 关键词：Bioreduction ; Trichothecium ; Acetophenone ; Fungus
- 刊名：Journal of Molecular Catalysis B: Enzymatic
- 出版年：2004
- 出版时间：February 2, 2004
- 年：2004
- 卷：27
- 期：2-3
- 页码：61-63
- 全文大小：52.0 K
文摘
Whole cells of the fungus Trichothecium were found to be an effective biocatalyst for the enantioselective bioreduction of acetophenone and its analogous compounds to their corresponding (R)-alcohols with good to excellent enantiomeric excesses (90–98 % ). The easy availability of the biocatalyst besides simple reaction conditions suggests the possible use of the present method for preparing important chiral alcohols.