New wedelolides, (9R)-eudesman-9,12-olide δ-lactones, from Wedelia trilobata
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- 作者：Toan Phan Duca ; Truong Van Nguyen Thiena ; Akino Jossangb ; Phi Phung Nguyen Kima ; Philippe Grellierc ; Ginette Jaureguiberryc ; Quang Ton Thata ; b ; c ; ttquang@hcmus.edu.vn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Wedelolide ; Sesquiterpene δ-lactones ; Wedelia trilobata ; Asteraceae ; Antimalarial ; Plasmodium falciparum.
- 刊名：Phytochemistry Letters
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：17
- 期：Complete
- 页码：304-309
- 全文大小：655 K
文摘
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Two new wedelolides, (9R)-eudesman-9,12-olide δ-lactones, were isolated from leaves of Wedelia trilobata.
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Their structures were established by the interpretation of spectroscopic data.
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The wedelolides G (1) and H (2) marked antimalarial activity, in vitro, with IC50 values of 3.42, 5.96 μM.