Two-step synthesis of the bipyrrole precursor of prodigiosins

详细信息    查看全文

• 作者：Kenza Dairi ; Sasmita Tripathy ; Giorgio Attardo and Jean-Franç ; ois Lavallé ; e
• 关键词：Natural product ; Prodigiosins ; Tambjamines ; Haloformylation ; Bipyrrole ; Suzuki coupling
• 刊名：Tetrahedron Letters
• 出版年：2006
• 出版时间：10 April 2006
• 年：2006
• 卷：47
• 期：15
• 页码：2605-2606
• 全文大小：79 K

文摘

The key intermediate in the synthesis of prodigiosins, 4-methoxy-2,2′-bipyrrole-5-carboxaldehyde, has been prepared in two steps and 65 % overall yield from the commercially available 4-methoxy-3-pyrrolin-2-one.