Small Round Cell Tumors of Bone

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• 作者：Justin L. Seningen ; MD^a ; Carrie Y. Inwards ; MD^b ; ^{inwards.carrie@mayo.edu}
• 关键词：Ewing sarcoma ; Bone tumors ; Small round cell tumors ; Hematopoietic neoplasms ; Primary bone lymphoma ; Mesenchymal chondrosarcoma ; Small cell osteosarcoma
• 刊名：Surgical Pathology Clinics
• 出版年：2012
• 出版时间：March, 2012
• 年：2012
• 卷：5
• 期：1
• 页码：231-256
• 全文大小：12918 K

文摘

Diagnosing small round cell tumors (SCRTs) can be a difficult task for pathologists due to overlapping clinicopathologic features. This review highlights the clinical, radiographic, histologic, immunohistochemical, and genetic features of the most common SRCTs involving bone with an emphasis on differential diagnosis. SRCTs are a heterogeneous group of neoplasms characterized by poorly differentiated cells with small, blue, round nuclei and scant cytoplasm. They can occur as primary tumors in bone or soft tissue.