Very low risk ST-segment elevation myocardial infarction? It exists and may be easily identified

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• 作者：Felipe Dí ; ez-Delhoyo^a ; ¹ ; ² ; Marí ; a Jes&uacute ; s Valero-Masa^a ; ¹ ; ² ; Jes&uacute ; s Velá ; squez-Rodrí ; guez^a ; ¹ ; ² ; Carolina Devesa-Cordero^a ; ¹ ; ² ; Iago Sousa-Casasnovas^a ; ¹ ; ² ; Miriam Juá ; rez^a ; ¹ ; ² ; Rocí ; o Angulo-Llanos^a ; ¹ ; ² ; Francisco Ferná ; ndez-Avilé ; s^a ; ^b ; ¹ ; ² ; Manuel Martí ; nez-Sellé ; s^a ; ^b ; ^c ; ¹ ; ² ; ^{mmselles@secardiologia.es}
• 关键词：Length of stay ; ST-segment elevation myocardial infarction ; Outcomes ; Primary percutaneous coronary intervention ; Outcomes
• 刊名：International Journal of Cardiology
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：228
• 期：Complete
• 页码：615-620
• 全文大小：302 K
• 卷排序：228

文摘

Early discharge protocols have been proposed for ST-segment elevation myocardial infarction (STEMI) low risk patients despite the existence of few but significant cardiovascular events during mid-term follow-up. We aimed to identify a subgroup of patients among those considered low-risk in which prognosis would be particularly good.MethodsWe analyzed 30-day outcomes and long-term follow-up among 1.111 STEMI patients treated with reperfusion therapy.ResultsMultivariate analysis identified seven variables as predictors of 30-day outcomes: Femoral approach; age > 65; systolic dysfunction; postprocedural TIMI flow < 3; elevated creatinine level > 1.5 mg/dL; stenosis of left-main coronary artery; and two or higher Killip class (FASTEST). A total of 228 patients (20.5%), defined as very low-risk (VLR), had none of these variables on admission. VLR group of patients compared to non-VLR patients had lower in-hospital (0% vs. 5.9%; p < 0.001) and 30-day mortality (0% vs. 6.25%: p < 0.001). They also presented fewer in-hospital complications (6.6% vs. 39.7%; p < 0.001) and 30-day major adverse events (0.9% vs. 4.5%; p = 0.01). Significant mortality differences during a mean follow-up of 23.8 ± 19.4 months were also observed (2.2% vs. 15.2%; p < 0.001). The first VLR subject died 11 months after hospital discharge. No cardiovascular deaths were identified in this subgroup of patients during follow-up.ConclusionsAbout a fifth of STEMI patients have VLR and can be easily identified. They have an excellent prognosis suggesting that 24–48 h in-hospital stay could be a feasible alternative in these patients.