External validation of the pathological nodal staging score in upper tract urothelial carcinoma: A population-based study

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• 作者：Evanguelos Xylinas ; M.D.^a ; ^b ; ¹ ; Luis Kluth ; M.D.^a ; ^c ; ¹ ; Malte Rieken ; M.D.^a ; ^d ; Morgan Rouprê ; t ; M.D.^e ; Bashir Al Hussein Al Awamlh ; M.D.^a ; Thomas Clozel ; M.D.^a ; Maxine Sun ; M.D.^f ; Pierre I. Karakiewicz ; M.D.^f ; Mithat Gonen ; M.D.^g ; Shahrokh F. Shariat ; M.D.^a ; ^h ; ^{sfshariat@gmail.com}
• 关键词：Upper tract urothelial carcinoma ; Lymphadenectomy ; Validation ; Pathological nodal staging score ; SEER
• 刊名：Urologic Oncology: Seminars and Original Investigations
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：35
• 期：1
• 页码：33.e21-33.e26
• 全文大小：460 K
• 卷排序：35

文摘

To externally validate our previously developed pathological nodal staging model (pNSS) that allows quantification of the likelihood that a pathologically node-negative patient has, indeed, no lymph node metastasis (LNM). Similarly to the development cohort, the probability of missing a LNM decreased as the number of nodes examined increased in the validation cohort. The probability of having a positive node increased with advancing pathological T stage in both cohorts. We externally validated in a population-based database our previous pNSS, which could help the clinical decision-making regarding adjuvant chemotherapy administration.