A derivative of Mycobacterium smegmatis mc²155 that lacks the duplicated chromosomal region

详细信息    查看全文

• 作者：Digby F. Warner ; Gilles Etienne ; Xiao-Ming Wang ; Limenako G. Matsoso ; Stephanie S. Dawes ; Karine Soetaert ; Neil G. Stoker ; Jean Content ; Valerie Mizrahi
• 关键词：Chromosomal duplication
• 刊名：Tuberculosis
• 出版年：2006
• 出版时间：November 2006
• 年：2006
• 卷：86
• 期：6
• 页码：438-444
• 全文大小：226 K

文摘

The genome of Mycobacterium smegmatis mc²155 contains a 56 kb duplicated region. We isolated a mutant of mc²155 lacking this duplication (ΔDRKIN). This mutation did not affect the growth rate, surface properties or transformation efficiency of the organism, confirming the potential utility of ΔDRKIN for the study of genes contained within the duplicated region.