Astragaloside IV inhibits breast cancer cell invasion by suppressing Vav3 mediated Rac1/MAPK signaling

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• 作者：Ke Jiang ; Qing Lu ; Qiong Li ; Yajie Ji ; Weili Chen ; Xiaohong Xue ; ^{xiaohong_xue@126.com}
• 关键词：Astragaloside IV ; Breast cancer cells ; Vav3 ; Rac1/MAPK signaling
• 刊名：International Immunopharmacology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：42
• 期：Complete
• 页码：195-202
• 全文大小：2239 K
• 卷排序：42

文摘

AS-IV inhibits the viability and invasive potential of breast cancer cells. AS-IV inhibits Vav3 expression and Rac1/MAPK activation. AS-IV treatment inhibits tumor growth and metastasis in vivo.