Impact of maternal diabetes type 1 on proliferative potential, differentiation and apoptotic activity in villous capillaries of term placenta
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- 作者：Marie Jirkovská ; a ; mjirk@lf1.cuni.cz" class="auth_mail" title="E-mail the corresponding author ; Tomá ; &scaron ; Kučeraa ; Veronika Dvořá ; ková ; a ; Martin Jadrní ; čeka ; Milena Moravcová ; b ; Zdeněk Žižkab ; Vratislav Krejčí ; b
- 关键词：Caspase 3 ; Chorangiosis ; Diabetes ; Ki67 ; Nestin ; Placenta
- 刊名：Placenta
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：40
- 期：Complete
- 页码：1-7
- 全文大小：1311 K
文摘
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The proliferation, maturation and apoptosis in villous capillaries was compared between normal and diabetic placenta.
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Maternal diabetes mellitus is associated with lower proliferative ability and delayed differentiation of capillaries.
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The placenta in maternal diabetes displays lower potential to comply fetal requirements in the final stage of pregnancy.