Plasmid-mediated resistance and virulence mechanisms in the private health sector in KwaZulu-Natal, South Africa: An investigation of methicillin resistant Staphylococcus aureus (MRSA) clinical isolates collected during a three month period
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- 作者：Daniel G. Amoakoa ; Linda A. Besterb ; besterl@ukzn.ac.za" class="auth_mail" title="E-mail the corresponding author ; Anou M. Somboroa ; Sooraj Baijnathc ; Chetna N. Govindd ; Sabiha Y. Essacka
- 关键词：MRSA ; plasmids ; PCR ; PFGE
- 刊名：International Journal of Infectious Diseases
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：46
- 期：Complete
- 页码：38-41
- 全文大小：580 K
文摘
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Plasmid-mediated resistance and virulence mechanisms in MRSA were detected in KZN, South Africa.
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Plasmids were extracted and MRSA confirmed by the presence of mecA gene.
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The isolates were subjected to antimicrobial susceptibility testing.
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Molecular characterization of common resistance genes and virulence factors were determined by PCR.
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The genetic relatedness between the isolates was determined by PFGE giving an indication of similar circulating MRSA clones in the KZN province.