Synthesis and characterization of polycaprolactone for anterior cruciate ligament regeneration

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• 作者：Ayse Cansu Gurlek ; Burcu Sevinc ; Ece Bayrak ; Cevat Erisken ; ^{cerisken@etu.edu.tr}
• 关键词：Polycaprolactone ; Synthesis ; Anterior cruciate ligament ; Biomechanics ; Tissue engineering
• 刊名：Materials Science and Engineering: C
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：71
• 期：Complete
• 页码：820-826
• 全文大小：945 K
• 卷排序：71

文摘

Synthesis of polycaprolactone (PCL) via ring opening polymerization of ε-caprolactone and ammonium heptamolybdate is reported. Nanofiber scaffolds were produced from synthesized and commercial PCL. Scaffolds were biomechanically compared to native anterior cruciate ligament (ACL) tissue harvested from sheep. The synthesized PCL is similar to its commercial counterpart in terms of chemistry, surface morphology and mechanical properties. The synthesized PCL showed weaker mechanical properties visa vis native ACL tissue in terms of ultimate stress, and elastic modulus.