Prognostic importance of human papillomavirus (HPV) and p16 positivity in squamous cell carcinoma of the vulva treated with radiotherapy
详细信息 查看全文
- 作者：Larissa J. Leea ; f ; llee@lroc.harvard.edu" class="auth_mail" title="E-mail the corresponding author ; Brooke Howittb ; f ; Paul Catalanod ; f ; Cynthia Tanakaa ; Rita Murphya ; Nicole Cimbaka ; Rebecca DeMariaa ; Paula Bua ; Christopher Crumb ; f ; Neil Horowitzc ; f ; Ursula Matulonise ; f ; Akila N. Viswanathana ; f
- 关键词：Vulvar cancer ; Human papillomavirus ; Radiotherapy ; p16
- 刊名：Gynecologic Oncology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：142
- 期：2
- 页码：293-298
- 全文大小：359 K
文摘
- •
We evaluated HPV genotype, p16 status and outcome for vulvar SCC treated with RT.
- •
HPV or p16 positivity was associated with better PFS and fewer in-field relapses.
- •
HPV status is prognostic for women with vulvar SCC treated with radiotherapy.