Controllable cell electroporation using microcavity electrodes

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• 作者：Xiaoling Zhang^a ; ^bAuthor Vitae ; Ning Hu^a ; ^{huning@cqu.edu.cn}Author Vitae ; Xi Chen^aAuthor Vitae ; Ting Fan^aAuthor Vitae ; Zhenyu Wang^cAuthor Vitae ; Xiaolin Zheng^aAuthor Vitae ; Jun Yang^a ; ^{bioyangjun@cqu.edu.cn}Author Vitae ; Shizhi Qian^d ; ^{sqian@odu.edu}Author Vitae
• 关键词：Electro-fusion ; Transmembrane potential ; Microelectrode ; Microcavity ; Myoblast cell
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：240
• 期：Complete
• 页码：434-442
• 全文大小：2300 K
• 卷排序：240

文摘

Controllable electroporation of cells was achieved using microcavity electrodes. An optimized microcavity electrode for cell electroporation/electro-fusion was obtained. A cell electroporation model was developed and validated. High-yield electro-fusion in a microfluidic device with microcavity electrodes was achieved.