Frontline treatment of acute myeloid leukemia in adults

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• 作者：Gevorg Tamamyanp>ap>p> ; p>p>bp>p> ; p>p>gevorgtamamyan@gmail.comp>Author Vitae ; Tapan Kadiap>ap>Author Vitae ; Farhad Ravandip>ap>Author Vitae ; Gautam Borthakurp>ap>Author Vitae ; Jorge Cortesp>ap>Author Vitae ; Elias Jabbourp>ap>Author Vitae ; Naval Daverp>ap>Author Vitae ; Maro Ohanianp>ap>Author Vitae ; Hagop Kantarjianp>ap>Author Vitae ; Marina Konoplevap>ap>Author Vitae
• 关键词：Acute myeloid leukemia ; Frontline treatment ; High dose Ara-C ; Nucleoside analogues
• 刊名：Critical Reviews in Oncology/Hematology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：110
• 期：Complete
• 页码：20-34
• 全文大小：2297 K
• 卷排序：110

文摘

AML is a remarkably heterogeneous disease. Novel treatment strategies improved outcomes in selected genetic subsets of AML. Higher dose Ara-C based regimens showed to be superior over “7 + 3” regimens. Most centers still use “7 + 3” regimen and greater awareness will improve the outcome.