Schwann cells and their transcriptional network: Evolution of key regulators of peripheral myelination
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- 作者：C. Claus Stolt ; Michael Wegner ; michael.wegner@fau.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Schwann cell ; Myelin ; Transcription factors ; Regulatory circuits ; Neofunctionalization ; Sox proteins
- 刊名：Brain Research
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：1641
- 期：part_PA
- 页码：101-110
- 全文大小：1379 K
文摘
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The regulatory network in Schwann cells is a new vertebrate invention.
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Sox10, Oct6 and Krox20 act as central transcriptional regulators of peripheral myelination.
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Acquisition of regulatory functions likely involved neofunctionalization.