KMnO₄-mediated direct C2-selective C−H arylation of quinoline N-oxides with aromatic hydrazines

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• 作者：Jin-Wei Yuan ; ^{yuanjinweigs@126.com} ; Wei-Jie Li ; Yong-Mei Xiao
• 关键词：2-Arylquinoline N-oxide ; Arylhydrazine ; KMnO4-mediated ; Arylation ; Radical reaction
• 刊名：Tetrahedron
• 出版年：2017
• 出版时间：12 January 2017
• 年：2017
• 卷：73
• 期：2
• 页码：179-186
• 全文大小：745 K
• 卷排序：73

文摘

An efficient protocol for the synthesis of 2-arylquinoline N-oxides has been developed via KMnO4-mediated cross-coupling reaction of quinoline N-oxides with aromatic hydrazines in moderated to good yields. The reactions proceeded efficiently over a broad range of substrates with excellent regioselectivity and functional group tolerance.