Ganoderma atrum polysaccharide ameliorates ROS generation and apoptosis in spleen and thymus of immunosuppressed mice

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• 作者：Wen-Juan Li<sup>asup> ; Lu Li<sup>asup> ; Weng-Ya Zhen<sup>bsup> ; Le-Feng Wang<sup>csup> ; Meng Pan<sup>asup> ; Jia-Qian Lv<sup>asup> ; Fan Wang<sup>asup> ; Yu-Fei Yao<sup>dsup> ; Shao-Ping Nie<sup>asup> ; Ming-Yong Xie<sup>asup><sup> ; sup><sup>myxie@ncu.edu.cnsup>
• 关键词：Ganoderma atrum polysaccharide ; Immune organ ; Antioxidant enzymes ; Apoptosis ; Reactive oxygen specie
• 刊名：Food and Chemical Toxicology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：99
• 期：Complete
• 页码：199-208
• 全文大小：2099 K
• 卷排序：99

文摘

PSG-1 protected mice against CTX-mediated immune dysfunction in vivo. PSG-1 ameliorated oxidative damage in spleen and thymus of immunosuppressed mice. PSG-1 ameliorated apoptosis in spleen and thymus of immunosuppressed mice. Antioxidant activities play an important role in PSG-1-triggered immune benefits in immunosuppressed mice.