Binge ethanol in adulthood exacerbates negative outcomes following juvenile traumatic brain injury
详细信息 查看全文
- 作者：Kate Karelina ; Ekaterina.karelina@osumc.edu ; Kristopher R. Gaier ; Maya Prabhu ; Vanessa Wenger ; Timothy E.D. Corrigan ; Zachary M. Weil
- 关键词：TBI ; traumatic brain injury ; DCX ; doublecortin ; Iba-1 ; ionized calcium binding adaptor molecule 1 ; TLR4 ; toll like receptor 4 ; IL-1β ; interleukin 1 beta
- 刊名：Brain, Behavior, and Immunity
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：60
- 期：Complete
- 页码：304-311
- 全文大小：1557 K
- 卷排序：60
文摘
Binge levels of alcohol exacerbate TBI-induced neuropathology and inflammation. Binge alcohol produces mild learning impairments in injured mice. Injured, alcohol-treated mice have more ectopic DCX+ neurons in the dentate gyrus.