HE4 Serum Levels Are Associated with Heart Failure Severity in Patients With Chronic Heart Failure

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• 作者：Arnold Piek ; BSc¹ ; Wouter C. Meijers ; MD¹ ; Nicolas F. Schroten ; MD ; PhD¹ ; ³ ; Ron T. Gansevoort ; MD ; PhD² ; Rudolf A. de Boer ; MD ; PhD¹ ; Herman H.W. Silljé ; PhD¹ ; ^{h.h.w.sillje@umcg.nl}
• 关键词：HE4 ; WFDC2 ; chronic heart failure ; fibrosis
• 刊名：Journal of Cardiac Failure
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：23
• 期：1
• 页码：12-19
• 全文大小：368 K
• 卷排序：23

文摘

HE4 levels are elevated in patients with CHF. HE4 is associated with HF severity. HE4 levels correlated with HF biomarkers of fibrosis. HE4 levels were predictive of HF outcome in patients with CHF.