A Progenitor Cell Expressing Transcription Factor RORγt Generates All Human Innate Lymphoid Cell Subsets
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- 作者：Steven D. Scoville1 ; 6 ; Bethany L. Mundy-Bosse2 ; 6 ; Michael H. Zhang2 ; 6 ; Li Chen2 ; 6 ; Xiaoli Zhang3 ; 6 ; Karen A. Keller4 ; 6 ; Tiffany Hughes2 ; 6 ; Luxi Chen1 ; 6 ; Stephanie Cheng4 ; 6 ; Stephen M. Bergin1 ; 6 ; Hsiaoyin C. Mao2 ; 6 ; Susan McClory7 ; Jianhua Yu2 ; 6 ; William E. Carson III5 ; 6 ; Michael A. Caligiuri2 ; 6 ; michael.caligiuri@osumc.edu" class="auth_mail" title="E-mail the corresponding author ; Aharon G. Freud4 ; 6 ; aharon.freud@osumc.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Immunity
- 出版年：2016
- 出版时间：17 May 2016
- 年：2016
- 卷：44
- 期：5
- 页码：1140-1150
- 全文大小：2503 K
文摘
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All human innate lymphoid cell subsets express RORγt
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RORγt is expressed in a subset of CD34+CD45RA+ progenitors found in human SLT
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The human RORγt+CD34+CD45RA+ progenitor is restricted to ILC development