Exercise, but not antioxidants, reversed ApoE4-associated motor impairments in adult GFAP-ApoE mice
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- 作者：Kiran Chaudhari ; Jessica M. Wong ; Philip H. Vann ; Nathalie Sumien
- 关键词：Antioxidant ; ApoE ; Motor function ; Balance ; Strength ; Reflexes ; Exercise ; Vitamin C ; Vitamin E
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：305
- 期：Complete
- 页码：37-45
- 全文大小：1076 K
文摘
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- <p id="par0005">Profiling of motor behavior of adult GFAP-ApoE3 and GFAP-ApoE4 mice.p>
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- <p id="par0010">Determination of whether exercise training and antioxidant intake combined can improve further motor dysfunction.p>
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- <p id="par0015">Exercise was more efficient at improving motor function than antioxidants alone.p>
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- <p id="par0020">Combination of exercise and antioxidant did not lead to further beneficial effect, and had a moderate antagonistic interaction on strength measurements.p>