The chronic hepatotoxicity assessment of the herbal formula Zishen Yutai pill

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• 作者：Xiaoyan Xing^a ; ¹ ; Xuehong Deng^a ; ¹ ; Jinjin Shi^b ; Meishuang Zhang^c ; Guibo Sun^a ; Shimin Tang^c ; Qiuling Huang^d ; ^{13826214009@163.com} ; Xiaobo Sun^a ; ^{sun_xiaobo163@163.com}
• 关键词：Zishen Yutai pill ; Herbal formula ; Chronic hepatotoxicity ; Polygoni multiflori Radix ; No-observed-adverse-effect levels
• 刊名：Regulatory Toxicology and Pharmacology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：83
• 期：Complete
• 页码：81-88
• 全文大小：2081 K
• 卷排序：83

文摘

The liver toxicity of ZYP was assessed in both normal and the CCl4 induced chronic liver injury rats. No any mortality or abnormality in liver toxicity evaluation were noted in ZYP groups. No solid evidence of liver toxicity under ZYP exposure (9.450 g kg−1 d−1) was found.