Reconfiguration of hub-level community structure in depressions: A follow-up study via diffusion tensor imaging
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- 作者：Jiaolong Qina ; Haiyan Liub ; Maobin Weia ; Ke Zhaob ; Jianhuai Chenb ; Jingyu Zhua ; Xiangyu Shena ; Rui Yanb ; Zhijian Yaob ; c ; zjyao@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Qing Lua ; luq@seu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Major depressive disorder ; Antidepressant medication treatment ; Diffusion tensor image ; Hub-level community structure ; Connectome
- 刊名：Journal of Affective Disorders
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：207
- 期：Complete
- 页码：305-312
- 全文大小：917 K
文摘
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We conducted a longitudinal study of unipolar depressions before and after antidepressant medication treatment.
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We analyzed a hub-level community structure network by permutation network framework.
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Antidepressant medication (AM) therapy may promote the modulation of modular structure of hubs in the fronto-limbic circuit.
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The inter-module connections of the right medial superior frontal gyrus is a potential indicator for AM therapy response.