Early B Cell Factor 1 Regulates Adipocyte Morphology and Lipolysis in White Adipose Tissue
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- 作者：Hui Gao1 ; 6 ; Niklas Mejhert2 ; 6 ; Jackie A. Fretz3 ; Erik Arner2 ; 4 ; Silvia Lorente-Cebriá ; n2 ; Anna Ehrlund2 ; Karin Dahlman-Wright1 ; 5 ; Xiaowei Gong1 ; Staffan Strö ; mblad1 ; Iyadh Douagi2 ; Jurga Laurencikiene2 ; Ingrid Dahlman2 ; Carsten O. Daub1 ; 4 ; Mikael Rydé ; n2 ; Mark C. Horowitz3 ; mark.horowitz@yale.edu" class="auth_mail ; Peter Arner2 ; peter.arner@ki.se" class="auth_mail
- 刊名：Cell Metabolism
- 出版年：3 June 2014
- 年：2014
- 卷：19
- 期：6
- 页码：981-992
- 全文大小：2514 K
文摘
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EBF1 mRNA, protein, and activity is reduced in human hypertrophic adipose tissue
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The EBF1 regulatory cistrome includes genes controlling lipolysis and adipogenesis
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Ebf1+/− mice display WAT hypertrophy and become insulin resistant on high-fat diet
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TNF伪 reduces and correlates negatively with EBF1 levels in vitro and in vivo