Natural potential neuroinflammatory inhibitors from Alhagi sparsifolia Shap.

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• 作者：Di Zhou^a ; ^b ; Hongyan Wei^c ; Zhe Jiang^d ; Xuezheng Li^d ; Kun Jiao^e ; Xiaoguang Jia^c ; Yue Hou^e ; ^{houyue@mail.neu.edu.cn} ; Ning Li^a ; ^b ; ^{liningsypharm@163.com}
• 关键词：Neuroinflammatory inhibitors ; Alhagi sparsifolia Shap. ; Effective chemical composition ; Overactivated microglial cells ; Neurodegenerative diseases
• 刊名：Bioorganic & Medicinal Chemistry Letters
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：27
• 期：4
• 页码：973-978
• 全文大小：877 K
• 卷排序：27

文摘

The anti-neuroinflammatory material basis of A. sparsifolia Shap. was clarified. SAR between the constituents and anti-neuroinflammatory activities was discussed. Compounds 16 and 33 were suggested to be potential neuroinflammation inhibitors.