Matrix metalloproteinase-9 plays a role in protecting zebrafish from lethal infection with Listeria monocytogenes by enhancing macrophage migration
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- 作者：Ying Shan ; Yikai Zhang ; Xunhui Zhuo ; Xiaoliang Li ; Jinrong Peng ; Weihuan Fang ; whfang@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Matrix metalloproteinase-9 ; Macrophage ; Migration ; Listeria monocytogenes ; Germ-free zebrafish ; Microarray
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：54
- 期：Complete
- 页码：179-187
- 全文大小：1479 K
文摘
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Transcriptomic analysis of germ-free zebrafish immersion-infected with Listeria.
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Mmp-9 was the most up-regulated gene following immersion infection with Listeria.
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Mmp-9 is a host defense factor to infection by mobilizing macrophage migration.
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Mmp-9 is involved in macrophage migration via a non-proteolytic activity.