Omics-based approaches reveal phospholipids remodeling of Rhizopus oryzae responding to furfural stress for fumaric acid-production from xylose
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- 作者：Xinrong Pan1 ; Huanhuan Liu1 ; Jiao Liu ; Cheng Wang ; Jianping Wen ; jpwen@tju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Furfural ; R. oryzae ; Fumaric acid ; Metabolomics ; Lipidomics
- 刊名：Bioresource Technology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：222
- 期：Complete
- 页码：24-32
- 全文大小：1759 K
文摘
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Furfural seriously inhibited R. oryzae (ATCC 20344) for fumaric acid fermentation.
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The metabolic response of R. oryzae to furfural was analyzed by metabolomics.
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Potential key phospholipids to resist furfural were identified by lipidomics.
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A great increase of fumaric acid titer was achieved by rational feeding.