Anti-ulcerogenic effect of cavidine against ethanol-induced acute gastric ulcer in mice and possible underlying mechanism
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- 作者：Weifeng Li liwf@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xiumei Wang ; Hailin Zhang ; Zehong He ; Wenbing Zhi ; Fang Liu ; Yu Wang ; Xiaofeng Niu ; niuxf@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cavidine ; Ethanol ; Gastric ulcer ; Oxidative stress ; Inflammation
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：38
- 期：Complete
- 页码：450-459
- 全文大小：1827 K
文摘
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Cavidine exerts a gastroprotective effect against ethanol-induced injury in mice.
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Cavidine reduces ethanol-induced inflammation and oxidative stress in gastric mucosa.
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Cavidine inhibits the NF-κB pathway in ethanol-induced gastric ulcer in mice.
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Cavidine increases the production of PGE2.
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