Herpesvirus infections in hematopoietic stem cell transplant recipients seropositive for human cytomegalovirus before transplantation
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- 作者：Jun Fan ; Min Jing ; Meifang Yang ; Lichen Xu ; Hanying Liang ; Yaping Huang ; Rong Yang ; Genyong Gui ; Huiqi Wang ; Shengnan Gong ; Jindong Wang ; Xuan Zhang ; Hong Zhao ; Hainv Gao ; Huihui Dong ; Weihang Ma ; Jianhua Hu ; hjianhua0825@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hematopoietic stem cell transplantation ; Herpesvirus ; Epstein&ndash ; Barr virus ; Human cytomegalovirus ; Human herpes virus type 6 ; Infection
- 刊名：International Journal of Infectious Diseases
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：46
- 期：Complete
- 页码：89-93
- 全文大小：347 K
文摘
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Human cytomegalovirus (HCMV)-seropositive (IgG-positive/IgM-negative) hematopoietic stem cell transplantation recipients exhibited a high rate of herpesvirus infections, particularly Epstein–Barr virus (EBV).
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Anti-thymocyte globulin and male sex were strongly associated with an increased risk of EBV infection.
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Graft-versus-host disease prophylaxis with prednisone was determined to affect both EBV and HCMV infections.
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Prior infection with EBV was shown to promote human herpes virus type 6 infection.