Glucose enhances rat islet function via stimulating CART expression
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- 作者：Wan Xu1 ; Yuqing Zhang1 ; Mengyao Bai ; Feiye Zhou ; Ruyuan Deng ; Xueying Ji ; Juan Zhang ; Yun Liu ; Libin Zhou ; libinzhou99@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Xiao Wang ; wangxiao1976@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cocaine- and amphetamine-regulated transcript ; Islet function ; Glucose ; Type 2 diabetes
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：2 December 2016
- 年：2016
- 卷：481
- 期：1-2
- 页码：84-89
- 全文大小：750 K
文摘
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Glucose time- and dose-dependently stimulates CART mRNA expression in rat islets.
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Glucose upregulates CART expression through cAMP signaling pathway.
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CART overexpression amplifies insulin secretion in rat islets.