Development of biomimetic nanocomposites as bone extracellular matrix for human osteoblastic cells
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- 作者：Arundhati Bhowmicka ; Tapas Mitraa ; Arumugam Gnanamanib ; Manas Dasc ; Patit Paban Kundua ; ppk923@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Chitosan ; Polyvinyl alcohol ; Hydroxyapatite ; Zinc-oxide ; Nanocomposites
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：5 May 2016
- 年：2016
- 卷：141
- 期：Complete
- 页码：82-91
- 全文大小：2047 K
文摘
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Fabrication of interconnected macroporous bone extracellular matrix (BEMs) containing CTS/PVA/HAP-ZnO.
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Tensile strengths and porosities of BEMs were similar to human cancellous bone.
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BEMs showed good water uptake, antimicrobial, and biodegradable properties.
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High blood compatibility of BEMs was observed with hemolytic assay.
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BPMs promoted osteoblastic MG-63 cells proliferation and showed cytocompatibility.