- 作者：Kefu Cai ; Tian Xu ; Lihua Shen ; Yaohui Ni ; Qiuhong Ji ; charlsone@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Coil embolization ; Fever ; Intracranial aneurysm ; Risk factors
- 刊名：World Neurosurgery
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：88
- 期：Complete
- 页码：49-53
- 全文大小：3122 K
Methods
Patients undergoing endovascular coiling to treat subarachnoid hemorrhage in Nantong University between November 2011 and September 2014 were retrospectively reviewed. Postoperative temperature and patient demographic data, admission status, characteristic features of aneurysms, and endovascular coiling procedure were documented and analyzed. There were 336 consecutive patients included in this study, and 111 were classified as febrile (tympanic temperature >38.3°C for at least 2 consecutive days).
Results
Univariate analysis demonstrated that age, interval from onset of subarachnoid hemorrhage to operation, history of hypertension and smoking, Hunt and Hess grade, Fisher grade, temperature before coiling, leukocyte count on admission, and infectious complications were correlated with postoperative fever. Five variables were independent risk factors to predict fever by multivariate logistic regression: age >70 years (odds ratio [OR] = 2.6, 95% confidence interval [CI] = 1.2–5.6), Fisher grade 3 or 4 (OR = 2.2, 95% CI = 1.1–4.3), leukocyte count >10,000/mm3 on admission (OR = 2.3, 95% CI = 1.3–4.0), temperature >37.5°C before coiling (OR = 4.6, 95% CI = 2.0–10.7), and infectious complications (OR = 4.4, 95% CI = 2.2–8.6).
Conclusions
Postoperative fever after coil embolization was predicted by changeable and unchangeable risk factors in subarachnoid hemorrhage. However, characteristic features of aneurysms and the coiling procedure had no impact on development of postoperative fever. Preventing any infectious complications, lowering temperature before embolization, and draining bloody cerebrospinal fluid may assist in the prevention of subsequent fever.