Whole Eye Axial Biometry During Accommodation Using Ultra-long Scan Depth Optical Coherence Tomography

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• 作者：Jianguang Zhong^a ; ^bAuthor Vitae ; Aizhu Tao^a ; ^c ; Zhe Xu^a ; ^c ; Hong Jiang^b ; Yilei Shao^a ; ^c ; Huicheng Zhang^b ; Che Liu^d ; Jianhua Wang^a ; ^{jwang3@med.miami.edu" class="auth_mail}Author Vitae
• 刊名：American Journal of Ophthalmology
• 出版年：May, 2014
• 年：2014
• 卷：157
• 期：5
• 页码：1064-1069.e2
• 全文大小：887 K

文摘

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Purpose

To investigate changes of whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography (UL-OCT).

Design

Prospective, observational case series.

Methods

Twenty-one adult subjects were enrolled. Using UL-OCT, the left eye of each subject was imaged with relaxed diopters (0 D) and accommodative stimuli (+6 D). Full eye biometry included central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness, vitreous length, and axial length (AL).

Results

During accommodation (+6 D), the axial biometry of the whole eye changed significantly. Compared to the rest state, ACD at the accommodative state decreased significantly from 3.128 卤 0.305聽mm to 2.961 卤 0.298聽mm (paired t test, P < .001). The lens thickness increased significantly from 3.723 卤 0.237聽mm to 3.963 卤 0.234聽mm (P < .001). The vitreous length decreased significantly from 17.129 卤 0.864聽mm to 17.057 卤 0.848聽mm (P < .001). AL was 24.519 卤 0.917聽mm at the rest state and increased to 24.545 卤 0.915聽mm with聽+6 D accommodation stimulus. The elongated AL of 26.1 卤 13.4聽渭m between the rest and accommodative states was significant (P < .001).

Conclusions

During accommodation, whole eye axial biometry changed, including a decrease in ACD and vitreous length and an increase in lens thickness and AL. UL-OCT provides an alternative method that聽is suitable for full eye biometry during accommodation.