Resveratrol preconditioning protects hepatocytes against hepatic ischemia reperfusion injury via Toll-like receptor 4/nuclear factor-κB signaling pathway in vitro and in vivo
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- 作者：Diao Hea ; Zhen Guoa ; Jun-Liang Pua ; Dao-Feng Zhenga ; Xu-Fu Weia ; Rui Liua ; Cheng-Yong Tangb ; tcyongwzj@163.com" class="auth_mail" title="E-mail the corresponding author ; Zhong-Jun Wua ; wzjtcy@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hepatic ischemia reperfusion injury ; Resveratrol ; TLR4/NF-κB pathway ; Inflammatory
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：201-209
- 全文大小：1831 K
文摘
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Resveratrol protects hepatocytes and rats from hepatic ischemia reperfusion injury.
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Resveratrol inhibits the activity of TLR4/NF-κB in hepatocytes.
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Effect of resveratrol on BRL-3A cells is concentration-dependent.
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Hepatocytes modulate hepatic ischemia reperfusion-induced inflammation and injury.