TGF-B2 and soluble p55 TNFR modulate VCAM-1 expression in glioma cells and brain derived endothelial cells

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• 作者：Chen ; T.C. ; Hinton ; D.R. ; Yong ; V.W. ; Hofman ; F.M.
• 关键词：Brain microvessel endothelium ; Soluble TNFR ; VCAM-1 ; TGF-B2 ; Gliomas
• 刊名：Journal of Neuroimmunology
• 出版年：1997
• 出版时间：March, 1997
• 年：1997
• 卷：73
• 期：1-2
• 页码：155-161
• 全文大小：656 K

文摘

Transforming growth factor beta-2 (TGF-B2) is secreted by glioma cells and is known to decrease leukocyte–endothelium interaction. TGF-B2 alone and in conjunction with soluble tumor necrosis factor (TNF) p55 receptor, was found to decrease the expression of TNF induced VCAM-1 on the malignant glioma cell line A-172 and human cerebral microvessel endothelial (CNS-EC) cells. Co-culture of A-172 glioma cells led to a decrease in VCAM-1 expression; this effect on CNS-EC in co-culture could be simulated by glioma supernatant alone. These results suggest that malignant gliomas, by secreting TGF-B2 and releasing soluble TNF receptors, modulate adhesion molecules. Publisher: Elsevier Science Language of Publication: English Item Identifier: S0165-5728(96)00190-7 Publication Type: Article ISSN: 0165-5728 Cited by:

1. Yu, D.L.; Tian, Y.J.; He, J.L.; Xiao, F.R.; Wang, T.S.; Li, D.C.; Li, L.; Zheng, G.; Yanagisawa, O.,""Preparation of CN_x/TiN_y multilayers by ion beam sputtering""Journal of Crystal Growth2001pp. 303-311
   Bibliographic PageFull Text
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   Bibliographic PageFull Text
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   fuananb"">Bibliographic Pagefuananb&form=pdf&file=file.pdf"">Full Text
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   Bibliographic PageFull Text
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   Bibliographic PageFull Text
6. Wang, E.G.,""Research on carbon nitrides""Progress in Materials Science1997pp. 241-298
   Bibliographic PageFull Text
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   Bibliographic PageFull Text
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   Bibliographic PageFull Text
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    Bibliographic PageFull Text
11. Leonhardt, A.; Gruger, H.; Selbmann, D.; Arnold, B.; Thomas, J.,""Preparation of CN_x-phases using plasma-assisted and hot filament chemical vapour deposition""Thin Solid Films1998pp. 69-73
    Bibliographic PageFull Text
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    Bibliographic PageFull Text
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    Bibliographic PageFull Text
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    Bibliographic PageFull Text
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    Bibliographic PageFull Text
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Footnotes:

1. Invited paper presented at the Int. Conf. on Metallurgical Coatings and Thin Films, ICMCTF 98, San Diego, April 1998. Dedicated to our colleague and friend, Professor Dr. Jan Janca at the occasion of his 60th birthday.