Immunoregulatory effects of sirolimus vs. tacrolimus treatment in kidney allograft recipients
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- 作者：Nianqiao Gong1 ; Zhishui Chen1 ; Jing Wang1 ; Aifang Fang ; Yonghai Li ; Ying Xiang ; Changsheng Ming ; Weijie Zhang ; wjzhang@medmail.com.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Kidney transplantation ; Regulatory T cells ; Sirolimus ; Tacrolimus
- 刊名：Cellular Immunology
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：297
- 期：2
- 页码：87-93
- 全文大小：1598 K
文摘
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Comparing immunoregulatory effects of sirolimus vs. tacrolimus in renal recipients.
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Sirolimus maintained Tregs populations while tacrolimus did not.
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Both sirolimus and tacrolimus did not interfere with the proportions of Bregs.
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PRA and frequency of Th1/2 cells were similar receiving sirolimus vs. tacrolimus.
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