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Microenvironmental changes in the progression from adenocarcinoma in situ to minimally invasive adenocarcinoma and invasive lepidic predominant adenocarcinoma of the lung
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文摘

The cancer cells and stromal cells are immunostained in LPA.

Invasive potential of cancer cells is increased in noninvasive component of MIA.

At the progression from MIA to LPA-S, microenvironmental molecular changes occur.

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